SES Logo

SYSTEMIC ENZYME SUPPORT.org

 

Immunological aspects of systemic enzyme therapy (SET) in the complex treatment of recurrent nephrolithiasis.

Borisov A.V., Ukhal M.I., Kabak Yu.A., Borisov S.A. Immunological aspects of systemic enzyme therapy (SET) in the complex treatment of recurrent nephrolithiasis. 1st National Congress of the Ukraine on Immunology, Allergology, and Immunorehabilitation. Odessa State Medical University. Russian version

Treatment of 50 patients suffering from nephrolithiasis, complicated by a chronic pyelonephritis in the active stage of inflammation was studied. Clinical status, urinary concretions, as well as immunological examination (E-RFC, T-helpers, T-suppressors and their ratio) and humoral immunity parameters (EAC-RFC , serum immunoglobulins, CIC) were examined. Additionally, NBT-test, phagocytary activity and index and complement system were studied. 20 patients, treated by an antiinflammatory therapy and surgery, received also Phlogenzym (2 tbl. 4 times a day for 4 weeks). After the finishing of a complex therapy patients were examined again and results were compared to those with and without Phlogenzym administration. Patients treated by Phlogenzym showed:
    increase in total T-lymphocyte population;
    normalization of T-helpers/T-suppressors ratio;
    decreased CIC level;
    normalization of neutrophil intracellular bactericidal systems.
Positive immunological changes correlated with a favourable dynamics of various clinical parameters:
    non-complicated healing of postsurgical wound;
    no chronic pyelonephritis deterioration;
    faster functional and anatomical patency of urinary tract;
    marked decrease of concretion relapses - 1-year-observation